Naoya Nakamura Selected Research

Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)

9/2018	Classic Hodgkin Lymphoproliferative Diseases Clonally Unrelated to B-Chronic Lymphocytic Leukemia Successfully Treated with Bendamustine Plus Rituximab.
1/2017	Chronic lymphocytic leukemia/small lymphocytic lymphoma with t (2;18) (p12;q21) accompanied by a cutaneous nodule with histological features of diffuse large B-cell lymphoma.
7/2013	Over-expression of BACH2 is related to ongoing somatic hypermutation of the immunoglobulin heavy chain gene variable region of de novo diffuse large B-cell lymphoma.
1/2012	Presence of immunoglobulin heavy chain rearrangement in so-called IgG4-related plasma cell granuloma of the eyelid.
2/2010	Presence of immunoglobulin heavy chain rearrangement in so-called "plasma cell granuloma of the lung".
7/2009	Duodenal and nodal follicular lymphomas are distinct: the former lacks activation-induced cytidine deaminase and follicular dendritic cells despite ongoing somatic hypermutations.
4/2007	Demonstration of chimeric DNA of bcl-2 and immunoglobulin heavy chain in follicular lymphoma and subsequent Hodgkin lymphoma from the same patient.
3/2005	Primary breast diffuse large B-cell lymphoma shows a non-germinal center B-cell phenotype.
1/2005	CD5+ diffuse large B-cell lymphoma consists of germline cases and hypermutated cases in the immunoglobulin heavy chain gene variable region.
5/2004	HBL-3 cell line, derived from precursor B-cell lymphoblastic leukemia, lacks somatic hypermutation of immunoglobulin heavy chain variable region genes.

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Naoya Nakamura Research Topics

Disease

52	Neoplasms (Cancer) 01/2022 - 04/2002
30	Lymphoma (Lymphomas) 01/2022 - 09/2002
22	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2022 - 06/2002
16	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022 - 09/2002
10	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2019 - 09/2002
8	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2022 - 05/2003
7	Hodgkin Disease (Hodgkin's Disease) 01/2022 - 07/2005
7	Disease Progression 07/2021 - 04/2010
7	Carcinoma (Carcinomatosis) 04/2021 - 04/2009
7	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 07/2009 - 04/2002
6	Adenocarcinoma 08/2020 - 05/2009
6	T-Cell Lymphoma (Lymphoma, T Cell) 01/2019 - 06/2002
5	Multiple Myeloma 01/2019 - 06/2004
5	Neoplasm Metastasis (Metastasis) 05/2018 - 01/2011
5	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 05/2013 - 03/2002
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 07/2021 - 03/2012
4	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2019 - 07/2005
4	Rheumatoid Arthritis 01/2018 - 01/2010
4	Autoimmune Diseases (Autoimmune Disease) 03/2012 - 04/2002
4	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2011 - 01/2005
3	Spontaneous Remission 01/2022 - 04/2007
3	Esophageal Squamous Cell Carcinoma 03/2021 - 09/2019
3	Lymphatic Metastasis 02/2020 - 01/2017
3	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 01/2020 - 04/2017
3	Neoplasms, Cystic, Mucinous, and Serous 03/2019 - 06/2013
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2019 - 05/2003
3	Anemia 01/2016 - 03/2004
3	Immunoglobulin G4-Related Disease 09/2015 - 01/2010
2	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 12/2021 - 12/2007
2	Multi-centric Castleman's Disease 10/2021 - 02/2016
2	Fibrosis (Cirrhosis) 10/2021 - 02/2016
2	Thrombocytopenia (Thrombopenia) 10/2021 - 02/2016
2	Fever (Fevers) 10/2021 - 02/2016
2	Edema (Dropsy) 10/2021 - 02/2016
2	Leukemia 07/2021 - 07/2009
2	Philadelphia Chromosome 07/2021 - 01/2020
2	Lung Neoplasms (Lung Cancer) 04/2021 - 02/2013
2	Testicular Neoplasms (Testicular Cancer) 03/2021 - 09/2019
2	Pancreatic Neoplasms (Pancreatic Cancer) 08/2020 - 04/2015
2	Neuroendocrine Tumors (Neuroendocrine Tumor) 02/2020 - 04/2009
2	Splenomegaly 01/2020 - 12/2018
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020 - 07/2005
2	Renal Cell Carcinoma (Grawitz Tumor) 12/2019 - 10/2019
2	Hypotension (Low Blood Pressure) 12/2018 - 01/2008
2	Abdominal Pain (Pain, Abdominal) 12/2018 - 02/2016
2	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 04/2018 - 04/2017
2	Large Granular Lymphocytic Leukemia 04/2018 - 03/2004
2	Breast Neoplasms (Breast Cancer) 07/2017 - 05/2009

Drug/Important Bio-Agent (IBA)

12	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 09/2018 - 06/2002
11	Proteins (Proteins, Gene)FDA Link 07/2021 - 08/2008
9	Immunoglobulins (Immunoglobulin)IBA 01/2020 - 04/2002
8	ParaffinIBA 01/2019 - 05/2003
7	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 01/2010
7	Cyclin D1IBA 12/2020 - 03/2002
6	Immunoglobulin G (IgG)IBA 01/2019 - 06/2004
6	Rituximab (Mabthera)FDA Link 09/2018 - 02/2011
5	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2002
5	Biomarkers (Surrogate Marker)IBA 07/2021 - 09/2019
5	AntigensIBA 03/2021 - 09/2002
5	SteroidsIBA 05/2019 - 01/2013
5	Formaldehyde (Formol)FDA Link 01/2019 - 05/2003
4	NectinsIBA 02/2020 - 04/2015
4	CyclinsIBA 01/2017 - 02/2007
4	Biological ProductsIBA 07/2014 - 03/2002
3	CateninsIBA 12/2021 - 04/2015
3	Dasatinib (BMS 354825)FDA Link 07/2021 - 01/2017
3	Cadherins (E-Cadherin)IBA 10/2018 - 12/2013
3	Prednisolone (Predate)FDA LinkGeneric 07/2017 - 11/2005
3	Cytidine DeaminaseIBA 01/2013 - 07/2009
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 12/2014
2	entecavir FDA Link 01/2022 - 01/2020
2	Reticulin (Reticular Fiber)IBA 10/2021 - 02/2016
2	Tyrosine Kinase InhibitorsIBA 07/2021 - 01/2017
2	Immune Checkpoint InhibitorsIBA 04/2021 - 11/2019
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 02/2021 - 01/2019
2	HLA Antigens (Human Leukocyte Antigens)IBA 08/2020 - 12/2014
2	LigandsIBA 01/2020 - 01/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 04/2007
2	Phosphotransferases (Kinase)IBA 01/2020 - 04/2014
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2019 - 03/2004
2	Azacitidine (5 Azacytidine)FDA Link 01/2019 - 01/2018
2	ChromatinIBA 10/2018 - 01/2018
2	fludarabineIBA 09/2018 - 01/2017
2	Anaplastic Lymphoma KinaseIBA 04/2018 - 04/2017
2	Cell Adhesion MoleculesIBA 07/2017 - 12/2013
2	Imatinib Mesylate (Gleevec)FDA Link 01/2017 - 03/2012
2	Hormones (Hormone)IBA 12/2015 - 08/2014
2	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2015 - 12/2014
2	Progesterone Receptors (Progesterone Receptor)IBA 04/2015 - 05/2009

Therapy/Procedure

15	Drug Therapy (Chemotherapy) 01/2022 - 11/2002
15	Therapeutics 07/2021 - 04/2007
5	Radiotherapy 07/2018 - 11/2002
3	Pancreatectomy 03/2019 - 05/2010
2	Hematopoietic Stem Cell Transplantation 07/2021 - 01/2019
2	Catheters 04/2021 - 06/2019
2	Splenectomy 12/2018 - 01/2009
2	Neoadjuvant Therapy 07/2018 - 07/2017
2	Mastectomy (Mammectomy) 07/2017 - 05/2009
2	Stem Cell Transplantation 07/2017 - 01/2011
2	Tonsillectomy 01/2017 - 04/2008